The Science behind Hoodia
There is growing evidence that Hoodia
works to supress the appetite. To start, for thousands of years the Bushmen of
South Africa having been eating Hoodia to fight off hunger during their long
Phytopharm reports clinical studies
with Hoodia P57
Phytopharm completed a double-blind,
placebo-controlled clinical study in overweight, but otherwise healthy
volunteers using Hoodia P57 extract from the Hoodia plant. Participants were
split into two groups, one received the P57 and the other received a placebo.
Each group was told to continue their normal diet and exercise. Phytopharm
reported results of the study as follows: When comparing the P57 group to the
Placebo group: The P57 group had a statistically significant reduction in
The P57 group had a statistically
significant reduction in body fat
The P57 had no adverse side effects
On average the P57 group ate about 1,000
calories a day less than those in the control group. These are impressive
results. See references below.
Brown University Medical School Research on Hoodia effects with Rats
Researchers at Brown University Medical
School performed studies in 2004. In these studies "Zucker Rats" were fed
Hoodia. Zucker Rats are special rats that are bred to be obese and diabetic.
Amazingly Zucker Rats that were fed Hoodia lost weight and even saw some
reversal of their diabetes. Anything that can stop a rat from eating is very
significant! (References Below)
- Van Heerden FR, Vleggaar R, Horak RM, Learmonth RA, Maharaj
V, Whittal RD. Pharmaceutical compositions having appetite suppression activity.
United States Patent 6,376,657, issued April 23, 2002.
- Tulp OL, Harbi NA, Mihalov J, DerMarderosian A. Effect of
Hoodia plant on food intake and body weight in lean and obese LA/Ntul//-cp rats.
FASEB J 2001 Mar 7;15(4):A404.
- Tulp OL, Harbi NA, DerMarderosian A. Effect of Hoodia plant
on weight loss in congenic obese LA/Ntul//-cp rats. FASEB J 2002 Mar
- Habeck M. A succulent cure to end obesity. Drug Discovery
Today, March 2002, pp 280-1.
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Courtesy of CBS 60 Minutes
“It's very different from diet stimulants
like Ephedra and Phenfen that are now banned because of dangerous side effects.
Hoodia doesn't stimulate at all. Scientists say it fools the brain by making you
think you’re full, even if you've eaten just a morsel. 60 Minutes Correspondent
Lesley Stahl reports.
So how did it work? Stahl says she had no after effects – no funny taste in her mouth,
no queasy stomach, and no racing heart. She also wasn't hungry all day, even
when she would normally have a pang around mealtime. And, she also had no desire
to eat or drink the entire day. "I'd have to say it did work," says Stahl”.
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